Risk Factors of Periventricular Leukomalacia (PVL) Re-Revisited 1052
نویسندگان
چکیده
منابع مشابه
A model of Periventricular Leukomalacia (PVL) in neonate mice with histopathological and neurodevelopmental outcomes mimicking human PVL in neonates
Periventricular leukomalacia (PVL), a brain injury affecting premature infants is commonly associated with cerebral palsy. PVL results from hypoxia-ischemia (HI) with or without infection and is characterized by white matter necrotic lesions, hypomyelination, microglial activation, astrogliosis, and neuronal death. It is important to study a PVL mouse model that mimics human PVL in symptomatolo...
متن کاملAnimal Models of Periventricular Leukomalacia
Periventricular leukomalacia, specifically characterized as white matter injury, in neonates is strongly associated with the damage of pre-myelinating oligodendrocytes. Clinical data suggest that hypoxia-ischemia during delivery and intrauterine or neonatal infection-inflammation are important factors in the etiology of periventricular leukomalacia including cerebral palsy, a serious case exhib...
متن کاملMouse Models of Periventricular Leukomalacia
We describe a protocol for establishing mouse models of periventricular leukomalacia (PVL). PVL is the predominant form of brain injury in premature infants and the most common antecedent of cerebral palsy. PVL is characterized by periventricular white matter damage with prominent oligodendroglial injury. Hypoxia/ischemia with or without systemic infection/inflammation are the primary causes of...
متن کاملFactors associated with epilepsy in children with periventricular leukomalacia.
Children with cerebral palsy associated with periventricular leukomalacia frequently develop unprovoked epileptic seizures. This article reports an analysis of risk factors for epilepsy in children with radiologically confirmed periventricular leukomalacia. This cohort was screened for epilepsy and for an array of clinical and demographic factors. Of 154 subjects with radiologically confirmed p...
متن کاملPontine hypoplasia in children with periventricular leukomalacia.
BACKGROUND AND PURPOSE The brain stem in patients with periventricular leukomalacia (PVL) appears smaller than normal on MR imaging, but few reports have described this feature, and the number of patients has been relatively small. The present study was conducted to examine the hypothesis that the pons in patients with PVL is smaller than normal. MATERIALS AND METHODS Using MR imaging, we exa...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-01073